HIV downregulates interferon-stimulated genes in primary macrophages

HIV is able to outpace the innate immune response, including that mediated by interferon (IFN), to establish a productive infection. Primary macrophages, however, may be protected from HIV infection by treatment with type I IFN before virus exposure. The ability of HIV to modulate the type I IFN-med...

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Bibliographic Details
Main Authors: Wie, S.H (Author), Duriez, Patrick J. (Author), Luong, T.Q (Author), Rought, S.E (Author), Beliakova-Bethell, N. (Author), Lozach, J. (Author), Corbeil, J. (Author), Kornbluth, R.S (Author), Richman, D.D (Author), Woelk, C.H (Author)
Format: Article
Language:English
Published: 2013-02-11.
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