HIV downregulates interferon-stimulated genes in primary macrophages
HIV is able to outpace the innate immune response, including that mediated by interferon (IFN), to establish a productive infection. Primary macrophages, however, may be protected from HIV infection by treatment with type I IFN before virus exposure. The ability of HIV to modulate the type I IFN-med...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2013-02-11.
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Subjects: | |
Online Access: | Get fulltext |