Direct and specific activation of human inward rectifier K+ channels by membrane phosphatidylinositol 4,5-bisphosphate

Many ion channels are modulated by phosphatidylinositol 4,5-bisphosphate (PIP(2)), but studies examining the PIP(2) dependence of channel activity have been limited to cell expression systems, which present difficulties for controlling membrane composition. We have characterized the PIP(2) dependenc...

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Bibliographic Details
Main Authors: D'Avanzo, Nazzareno (Author), Cheng, Wayland W.L (Author), Doyle, Declan A. (Author), Nichols, Colin G. (Author)
Format: Article
Language:English
Published: 2010-11-26.
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