Chemically modified siRNA: tools and applications
Chemical modification provides solutions to many of the challenges facing siRNA therapeutics. This review examines the various siRNA modifications available, including every aspect of the RNA structure and siRNA duplex architecture. The applications of chemically modified siRNA are then examined, wi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2008-10.
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| Subjects: | |
| Online Access: | Get fulltext |