Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes

BACKGROUND: Multiple genes have been implicated by association studies in altering inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more extensive disease and a particularly severe disease course. It is likely that genetic predisposition plays a more substantial ro...

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Bibliographic Details
Main Authors: Christodoulou, K. (Author), Wiskin, A.E (Author), Gibson, J. (Author), Tapper, W. (Author), Willis, C. (Author), Afzal, N.A (Author), Upstill-Goddard, R. (Author), Holloway, J.W (Author), Simpson, M.A (Author), Beattie, R.M (Author), Collins, A. (Author), Ennis, S. (Author)
Format: Article
Language:English
Published: 2013-07.
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