The release of basogranulin in response to IgE-dependent and IgE-independent stimuli: validity of basogranulin measurement as an indicator of basophil activation

Background: Basogranulin, the novel basophil granule protein recognized by the monoclonal antibody BB1, can be released by stimulation with anti-IgE antibody or calcium ionophore. However, the kinetics and regulation of its secretion are unknown. Objective: We quantified basogranulin and histamine r...

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Bibliographic Details
Main Authors: Mochizuki, Akinori (Author), McEuen, Alan R. (Author), Buckley, Mark G. (Author), Walls, Andrew F. (Author)
Format: Article
Language:English
Published: 2003-07.
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