Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans
?-latrotoxin (LTX), a 120 kDa protein in black widow spider venom, triggers massive neurotransmitter exocytosis. Previous studies have highlighted a role for both intrinsic pore-forming activity and receptor binding in the action of this toxin. Intriguingly, activation of a presynaptic G protein-cou...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2004-08-10.
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Subjects: | |
Online Access: | Get fulltext |