Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
Environmental constraints during early life result in phenotypic changes that can be associated with increased disease risk in later life. This suggests persistent alteration of gene transcription. DNA methylation, which is largely established in utero, provides a causal mechanism by which unbalance...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2005-06.
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| Subjects: | |
| Online Access: | Get fulltext |