Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: a negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?

In bone, angiogenesis must be initiated appropriately, but limited once remodelling or repair is complete. Our recent findings have supported a role for prostaglandins (PG), known modulators of osteoblast (OB) and endothelial cell (EC) behaviour, in facilitating VEGF-mediated paracrine communication...

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Bibliographic Details
Main Authors: Clarkin, Claire E. (Author), Garonna, Elena (Author), Pitsillides, Andrew A. (Author), Wheeler-Jones, Caroline P.D (Author)
Format: Article
Language:English
Published: 2008-10-15.
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