Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease

Chitin, the second most abundant polysaccharide on earth, is degraded by chitinases and chitobiases. The structure of Serratia marcescens chitobiase has been refined at 1.9 A resolution. The mature protein is folded into four domains and its active site is situated at the C-terminal end of the centr...

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Bibliographic Details
Main Authors: Tews, Ivo (Author), Perrakis, A. (Author), Oppenheim, A. (Author), Dauter, Z. (Author), Wilson, K. S. (Author), Vorgias, C. E. (Author)
Format: Article
Language:English
Published: 1996-07.
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