Heavily fluorinated carbohydrates as enzyme substrates: oxidation of tetrafluorinated galactose by galactose oxidase

Galactose oxidase (GOase) was shown to oxidise several C2/C3 fluorinated galactose analogues. Interestingly, the enzyme was able to distinguish between the 2,3-tetrafluorinated galactose and its epimeric glucose analogue, and this represents the first reported biotransformation of a heavily fluorina...

Full description

Bibliographic Details
Main Authors: Ioannou, Avgousta (Author), Cini, Elena (Author), Timofte, Roxana S. (Author), Flitsch, Sabine L. (Author), Turner, Nicholas J. (Author), Linclau, Bruno (Author)
Format: Article
Language:English
Published: 2011-09-13.
Subjects:
Online Access:Get fulltext
LEADER 01028 am a22001813u 4500
001 198499
042 |a dc 
100 1 0 |a Ioannou, Avgousta  |e author 
700 1 0 |a Cini, Elena  |e author 
700 1 0 |a Timofte, Roxana S.  |e author 
700 1 0 |a Flitsch, Sabine L.  |e author 
700 1 0 |a Turner, Nicholas J.  |e author 
700 1 0 |a Linclau, Bruno  |e author 
245 0 0 |a Heavily fluorinated carbohydrates as enzyme substrates: oxidation of tetrafluorinated galactose by galactose oxidase 
260 |c 2011-09-13. 
856 |z Get fulltext  |u https://eprints.soton.ac.uk/198499/1/__soton.ac.uk_ude_PersonalFiles_Users_jks1m11_mydocuments_Chemistry_REF%2520papers_In%2520progress_Bruno%2520cover%2520%252B%2520paper.pdf 
520 |a Galactose oxidase (GOase) was shown to oxidise several C2/C3 fluorinated galactose analogues. Interestingly, the enzyme was able to distinguish between the 2,3-tetrafluorinated galactose and its epimeric glucose analogue, and this represents the first reported biotransformation of a heavily fluorinated sugar 
655 7 |a Article