Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy
A distinct sub-group of B-cell precursor acute lymphoblastic leukemia, defined by intrachromosomal amplification of chromosome 21 (iAMP21), is restricted to older children and has been associated with a poor outcome. Accurate diagnosis is important for appropriate risk stratification for treatment....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2011-07-01.
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| Subjects: | |
| Online Access: | Get fulltext |