Mitochondrial dysfunction leads to telomere attrition and genomic instability
Mitochondrial dysfunction and oxidative stress have been implicated in cellular senescence, apoptosis, aging and aging-associated pathologies. Telomere shortening and genomic instability have also been associated with replicative senescence, aging and cancer. Here we show that mitochondrial dysfunct...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2002-10.
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| Subjects: | |
| Online Access: | Get fulltext |