Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells

Decreased uncoupling protein (UCP)3 is associated with insulin resistance in muscle of pre-diabetic and diabetic individuals, but the function of UCP3 remains unclear. Our goal was to elucidate mechanisms underlying the negative correlation between UCP3 and insulin resistance in muscle. We determine...

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Bibliographic Details
Main Authors: MacLellan, J. Darcy (Author), Gerrits, Martin F. (Author), Gowing, Adrienne (Author), Smith, Peter J.S (Author), Wheeler, Michael B. (Author), Harper, Mary-Ellen (Author)
Format: Article
Language:English
Published: 2005-08.
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