Differential suppression of tumor-specific CD8+ T cells by regulatory T cells

In the CT26 BALB/c murine model of colorectal carcinoma, depletion of regulatory T cells (Tregs) prior to tumor inoculation results in protective immunity to both CT26 and other BALB/c-derived tumors of diverse histological origin. In this paper, we show that cross-protection can be conferred by ado...

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Main Authors: James, Edward (Author), Yeh, Alex (Author), King, Cathy (Author), Korangy, Firouzeh (Author), Bailey, Ian (Author), Boulanger, Denise S. (Author), Van den Eynde, Benoît J. (Author), Murray, Nicholas (Author), Elliott, Tim J. (Author)
Format: Article
Language:English
Published: 2010-11-01.
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