Differential suppression of tumor-specific CD8+ T cells by regulatory T cells
In the CT26 BALB/c murine model of colorectal carcinoma, depletion of regulatory T cells (Tregs) prior to tumor inoculation results in protective immunity to both CT26 and other BALB/c-derived tumors of diverse histological origin. In this paper, we show that cross-protection can be conferred by ado...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2010-11-01.
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Subjects: | |
Online Access: | Get fulltext |