Lack of laminin ?1 in embryonic stem cell-derived cardiomyocytes causes inhomogeneous electrical spreading despite intact differentiation and function

Laminins form a large family of extracellular matrix (ECM) proteins, and their expression is a prerequisite for normal embryonic development. Herein we investigated the role of the laminin 1 chain for cardiac muscle differentiation and function using cardiomyocytes derived from embryonic stem cells...

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Main Authors: Malan, Daniela (Author), Reppel, Michael (Author), Dobrowolski, Radoslaw (Author), Roell, Wilhelm (Author), Smyth, Neil (Author), Hescheler, Juergen (Author), Paulsson, Mats (Author), Bloch, Wilhelm (Author), Fleischmann, Bernd K. (Author)
Format: Article
Language:English
Published: 2009-01-05.
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