Nramp1-functionality increases iNOS expression via repression of IL-10 formation
In mice, resistance to certain intracellular microbes depends on the expression of a late phagosomal protein termed natural-resistance associated macrophage protein 1 (Nramp1, Slc11a1). Nramp1-functionality is associated with alterations of cellular iron homeostasis and a sustained pro-inflammatory...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2008-11.
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| Subjects: | |
| Online Access: | Get fulltext |