Involvement of CELSR3 hypermethylation in primary oral squamous cell carcinoma

Involvement of CELSR3 hypermethylation in primary oral squamous cell carcinoma

Background: Promoter hypermethylation is a frequent epigenetic mechanism for gene transcription repression in cancer and is one of the hallmarks of the disease. Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) contributes to cell contact-mediated communication. Dysregulation of promoter methyl...

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Bibliographic Details
Main Authors: Abraham, T.M (Author), Froemming, G.R.A (Author), Khor, G.H (Author), Lin, T.K (Author), Zain, R.B (Author)
Format: Article
Language:English
Published: Asian Pacific Organization for Cancer Prevention 2016
Subjects:
Biomarker
Biomarkers, Tumor
cadherin
Cadherins
Carcinoma, Squamous Cell
cell surface receptor
CELSR3
Celsr3 protein, human
DNA
DNA methylation
DNA Methylation
DNA, Neoplasm
female
Female
gene expression regulation
Gene Expression Regulation, Neoplastic
genetics
human
Humans
Hypermethylation
male
Male
middle aged
Middle Aged
Mouth Neoplasms
mouth tumor
Oral squamous cell carcinoma
promoter region
Promoter Regions, Genetic
Receptors, Cell Surface
squamous cell carcinoma
tumor marker
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