S-substituted derivatives of 1,2,4-triazol-3-thiol as new drug candidates for type II diabetes

S-substituted derivatives of 1,2,4-triazol-3-thiol as new drug candidates for type II diabetes

The therapeutic applications of 1,2,4-triazoles motivated us to synthesize some new derivatives. Two series of S -substituted derivatives (8a–8j, 12a–12i) of 5- (1-[(4-chlorophenyl)sulfonyl]-3-piperidinyl )-4-phenyl-4 H -1,2,4-triazol-3-thiol (6) have been synthesized and evaluated for their biologi...

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Bibliographic Details
Main Authors: Adnan Ali Shah, S. (Author), Ashraf, M. (Author), Athar Abbasi, M. (Author), Jahan, B. (Author), Khan, F.A (Author), Lodhi, M.A (Author), Nafeesa, K. (Author), Rasool, S. (Author), Ur-Rehman, A. (Author), Zahra Siddiqui, S. (Author)
Format: Article
Language:English
Published: TUBITAK 2018
Subjects:
1
2
4-Triazole
Anti-α-glucosidase
Hemolytic activity
Sulfonamides
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