Potential Immunogenic Activity of Computationally Designed mRNA- and Peptide-Based Prophylactic Vaccines against MERS, SARS-CoV, and SARS-CoV-2: A Reverse Vaccinology Approach

Potential Immunogenic Activity of Computationally Designed mRNA- and Peptide-Based Prophylactic Vaccines against MERS, SARS-CoV, and SARS-CoV-2: A Reverse Vaccinology Approach

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The continued emergence of human coronaviruses (hCoVs) in the last few decades has posed an alarming situation and requires advanced cross-protective strategies against these pandemic viruses. Among these, Middle East Respiratory Syndrome coronavirus (MERS-CoV), Severe Acute Respiratory Syndrome cor...

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Bibliographic Details
Main Authors: Ansari, J.K (Author), Khan, A. (Author), Khan, T. (Author), Muhammad, K. (Author), Najmi, M.H (Author), Waheed, Y. (Author), Wei, D.-Q (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
chemistry
COVID-19
epitope
epitopes
Epitopes, B-Lymphocyte
Epitopes, T-Lymphocyte
human
Humans
MERS-CoV
messenger RNA
molecular docking
Molecular Docking Simulation
prevention and control
prophylactic vaccine
proteomics
Proteomics
RNA, Messenger
SARS-CoV
SARS-CoV-2
subunit vaccine
Vaccines, Subunit
Vaccinology
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