Permeability of the Perindopril Arginine under In Vitro Conditions across Caco-2 Monolayer and Biomimetic Phospholipid Membrane

Perindopril arginine (PA) as an angiotensin-converting enzyme (ACE) inhibitor is widely used in cardiovascular diseases, especially in systemic hypertension and heart failure. Although the pharmacokinetics of PA are well documented, there is no available detailed data on its permeation in in vitro c...

Full description

Bibliographic Details
Main Authors: Czaklosz, P. (Author), Gorniak, K. (Author), Ibragimow, I. (Author), Kus, M. (Author), Olejnik, A. (Author), Piotrowska-Kempisty, H. (Author), Skupin-Mrugalska, P. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Online Access:View Fulltext in Publisher