Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via in Vitro and in Vivo

Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via in Vitro and in Vivo

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Centella asiatica (C. asiatica) is one of the medicinal plants that has been reported to exert comprehensive neuroprotection in vitro and in vivo. In view of this, the present study was performed to investigate the effect of ethanolic extract of C. asiatica, designated as raw-extract of C. asiatica...

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Bibliographic Details
Main Authors: Adenan, M.I (Author), Hafiz, Z.Z (Author), Johari James, R.M (Author), Mohd Amin, M.A (Author), Salleh, M.Z (Author), Teh, L.K (Author)
Format: Article
Language:English
Published: MDPI AG, 2020
Subjects:
acetylcholinesterase
Acetylcholinesterase
animal
Animals
Anti-acetylcholinesterase
Anti-inflammatory
antiinflammatory agent
Anti-Inflammatory Agents
antioxidant
Antioxidant
Antioxidants
cell death
Cell Death
cell survival
Cell Survival
Centella asiatica
Centella asiatica extract
Chromatography, High Pressure Liquid
Dinoprostone
drug effect
glutathione
Glutathione
high performance liquid chromatography
human
Humans
In vitro
In vivo
inflammation
Inflammation
Lipopolysaccharides
metabolism
Mice
mouse
nitrite
Nitrites
oxidative stress
Oxidative Stress
pathology
prostaglandin E2
Rats, Sprague-Dawley
RAW 264.7 cell line
RAW 264.7 Cells
reactive oxygen metabolite
Reactive Oxygen Species
Sprague Dawley rat
triterpene
Triterpenes
tumor necrosis factor
Tumor Necrosis Factor-alpha
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