Inhibitory effect of triterpenoids from Dillenia serrata (Dilleniaceae) on prostaglandin e2 production and quantitative HPLC analysis of its koetjapic acid and betulinic acid contents

Inhibitory effect of triterpenoids from Dillenia serrata (Dilleniaceae) on prostaglandin e2 production and quantitative HPLC analysis of its koetjapic acid and betulinic acid contents

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The crude methanol extracts and fractions of the root and stem barks of Dillenia serrata Thunb. showed 64% to 73% inhibition on the production of prostaglandin E2 (PGE2) in lipopolysaccharide-induced human whole blood using a radioimmunoassay technique. Three triterpenoids isolated from the root bar...

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Bibliographic Details
Main Authors: Ahmat, N. (Author), Aladdin, N.-A (Author), Buang, F. (Author), Jalil, J. (Author), Jamal, J.A (Author), Jantan, I. (Author), Mohamad, H.F (Author), Muhammad, K. (Author), Sabandar, C.W (Author), Sahidin, I. (Author)
Format: Article
Language:English
Published: MDPI AG 2015
Subjects:
bark
betulic acid
biosynthesis
chemistry
cytology
Dillenia serrata
Dilleniaceae
Dinoprostone
HPLC
human
Humans
koetjapic acid
lipopolysaccharide
Lipopolysaccharides
metabolism
monocyte
Monocytes
Plant Bark
plant root
Plant Roots
prostaglandin E2
Prostaglandin E2
triterpene
Triterpenes
Triterpenoids
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