Synthesis of 4-methoxybenzoylhydrazones and evaluation of their antiglycation activity

Synthesis of 4-methoxybenzoylhydrazones and evaluation of their antiglycation activity

Show other versions (1)

A series of 4-methoxybenzoylhydrazones 1-30 was synthesized and the structures of the synthetic derivatives elucidated by spectroscopic methods. The compounds showed a varying degree of antiglycation activity, with IC50 values ranging between 216.52 and 748.71 M, when compared to a rutin standard (I...

Full description

Bibliographic Details
Main Authors: Choudhary, M.I (Author), Ismail, N.H (Author), Naz, H. (Author), Rahman, A.A (Author), Rasheed, S. (Author), Taha, M. (Author), Yousuf, S. (Author)
Format: Article
Language:English
Subjects:
4-methoxybenzoylhydrazones
AGEs
Antiglycation activity
article
chemical structure
Diabetes
drug effect
glycosylation
Glycosylation
hydrazone derivative
Hydrazones
IC 50
Inhibitory Concentration 50
Molecular Structure
Protein glycation inhibition
Rutin
structure activity relation
Structure-Activity Relationship
synthesis
Online Access:View Fulltext in Publisher
View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Similar Items