Evaluation of the bioactivity of novel spiroisoxazoline type compounds against normal and cancer cell lines

Evaluation of the bioactivity of novel spiroisoxazoline type compounds against normal and cancer cell lines

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The aim of this study was to investigate the in vitro cellular activity of novel spiroisoxazoline type compounds against normal and cancer cell lines from lung tissue (Hs888Lu), neuron-phenotypic cells (SH-SY5Y), neuroblastoma (SH-SY5Y), human histiocytic lymphoma (U937), lung cancer (A549), and leu...

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Bibliographic Details
Main Authors: Bathich, Y. (Author), Hamzah, A.S (Author), Najim, N. (Author), Shaameri, Z. (Author), Zain, M.M (Author)
Format: Article
Language:English
Subjects:
antineoplastic agent
Antineoplastic Agents
article
bioassay
Biological Assay
cell strain HL 60
cell strain U937
chemistry
Cytotoxicity
cytotoxin
Cytotoxins
degenerative disease
drug screening
Drug Screening Assays, Antitumor
HL-60 Cells
human
Humans
methodology
neoplasm
Neoplasms
Neurodegenerative Diseases
Neuroprotection
Neurotoxicity
Pyrrolidine
pyrrolidine derivative
Pyrrolidines
Spiroisoxazoline
U937 Cells
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