Brain-Implantable Multifunctional Probe for Simultaneous Detection of Glutamate and GABA Neurotransmitters: Optimization and In Vivo Studies

Brain-Implantable Multifunctional Probe for Simultaneous Detection of Glutamate and GABA Neurotransmitters: Optimization and In Vivo Studies

Imbalances in levels of glutamate (GLU) and gamma-aminobutyric acid (GABA) and their sub-second signaling dynamics occur in several brain disorders including traumatic brain injury, epilepsy, and Alzheimer’s disease. The present work reports on the optimization and in vivo testing of a silicon (Si)...

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Bibliographic Details
Main Authors: Arumugam, P.U (Author), Billa, S. (Author), Hossain, I. (Author), Moldovan, N. (Author), Murray, T.A (Author), Siddiqui, S. (Author), Yanamadala, Y. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Amino acids
biosensor
Biosensors
Brain
Calibration
GABA
Gamma-aminobutyric acids
glutamate
Glutamate
in vivo recording
In vivo recording
in-situ calibration
In-situ calibration
In-vivo
Microelectrodes
Multifunctional probes
Optimisations
Probes
Real time sensors
real-time sensor
Simultaneous detection
Vivo recordings
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