Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma

Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma

Malignant mesothelioma (MM) is a highly aggressive and resistant tumor. The prognostic role of key effectors of glycolytic metabolism in MM prompted our studies on the cytotoxicity of new inhibitors of glucose transporter type 1 (GLUT-1) and lactate dehydrogenase-A (LDH-A) in relation to ATP/NAD+ me...

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Bibliographic Details
Main Authors: Avan, A. (Author), Franczak, M.A (Author), Giovannetti, E. (Author), Granchi, C. (Author), Harasim, G. (Author), Jedrzejewska, A. (Author), Krol, O. (Author), Minutolo, F. (Author), Peters, G.J (Author), Smolenski, R.T (Author), Zaffaroni, N. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
anticancer treatment
cancer metabolism
chemoresistance
glucose transporter type 1
lactate dehydrogenase
malignant mesothelioma
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