ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression

Glioblastoma (GBM) is a malignant brain tumor, commonly treated with temozolomide (TMZ). Upregulation of A disintegrin and metalloproteinases (ADAMs) is correlated to malignancy; however, whether ADAMs modulate TMZ sensitivity in GBM cells remains unclear. To explore the role of ADAMs in TMZ resista...

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Bibliographic Details
Main Authors: Chen, J.-C (Author), Chong, Z.-Y (Author), Huang, C. (Author), Huang, H.-C (Author), Lee, I.-N (Author), Wu, Y.-P (Author), Yang, J.-T (Author)
Format: Article
Language:English
Published: MDPI 2023
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