N-Acetylaspartate and Choline Metabolites in Cortical and Subcortical Regions in Clinical High Risk Relative to Healthy Control Subjects: An Exploratory 7T MRSI Study

N-Acetylaspartate and Choline Metabolites in Cortical and Subcortical Regions in Clinical High Risk Relative to Healthy Control Subjects: An Exploratory 7T MRSI Study

N-acetylaspartate (NAA) and choline (Cho) are two brain metabolites implicated in several key neuronal functions. Abnormalities in these metabolites have been reported in both early course and chronic patients with schizophrenia (SCZ). It is, however, unclear whether NAA and Cho’s alterations occur...

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Bibliographic Details
Main Authors: Ferrarelli, F. (Author), Hetherington, H.P (Author), Huston, C.A (Author), Janssen, S.A (Author), Keihani, A. (Author), Mayeli, A. (Author), Moon, C.-H (Author), Rupp, J.S (Author), Sharma, K. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
aspartic acid
Aspartic Acid
brain cortical regions
choline
Choline
clinical high risk for psychosis
creatine
Creatine
DLPFC
hippocampus
Hippocampus
human
Humans
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
metabolism
NAA
N-acetylaspartate
nuclear magnetic resonance imaging
nuclear magnetic resonance spectroscopy
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