Lost by Transcription: Fork Failures, Elevated Expression, and Clinical Consequences Related to Deletions in Metastatic Colorectal Cancer

Among the structural variants observed in metastatic colorectal cancer (mCRC), deletions (DELs) show a size preference of ~10 kb–1 Mb and are often found in common fragile sites (CFSs). To gain more insight into the biology behind the occurrence of these specific DELs in mCRC, and their possible ass...

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Bibliographic Details
Main Authors: Martens, J.W.M (Author), Smid, M. (Author), Wilting, S.M (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher