Mood Regulatory Actions of Active and Sham Nucleus Accumbens Deep Brain Stimulation in Antidepressant Resistant Rats

Mood Regulatory Actions of Active and Sham Nucleus Accumbens Deep Brain Stimulation in Antidepressant Resistant Rats

The antidepressant actions of deep brain stimulation (DBS) are associated with progressive neuroadaptations within the mood network, modulated in part, by neurotrophic mechanisms. We investigated the antidepressant-like effects of chronic nucleus accumbens (NAc) DBS and its association with change i...

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Bibliographic Details
Main Authors: Berk, M. (Author), Kale, R.P (Author), Kouzani, A.Z (Author), Nguyen, T.T.L (Author), Price, J.B (Author), Sillitoe, R.V (Author), Tye, S.J (Author), Walder, K. (Author), Yates, N.J (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
deep brain stimualtion
depression
GSK3—glycogen synthase kinase 3
mania
mood
mTOR—mammalian target of rapamycin
nucleus accumbens
rodent
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