Early Life Stress Promotes Heroin Seeking But Does Not Alter the Excitability of Insular Pyramidal Cells Targeting the Nucleus Accumbens

A number of retrospective studies have demonstrated adverse childhood experiences are associated with increased vulnerability to substance use disorders, including opioid use disorders (OUDs). These adverse childhood experiences, also referred to as early life stress (ELS), can be modeled in laborat...

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Bibliographic Details
Main Authors: Leyrer-Jackson, J.M (Author), Nagy, E.K (Author), Olive, M.F (Author), Overby, P.F (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
rat
Online Access:View Fulltext in Publisher