Non-thermal Electroporation Ablation of Epileptogenic Zones Stops Seizures in Mice While Providing Reduced Vascular Damage and Accelerated Tissue Recovery

Non-thermal Electroporation Ablation of Epileptogenic Zones Stops Seizures in Mice While Providing Reduced Vascular Damage and Accelerated Tissue Recovery

In epilepsy, the most frequent surgical procedure is the resection of brain tissue in the temporal lobe, with seizure-free outcomes in approximately two-thirds of cases. However, consequences of surgery can vary strongly depending on the brain region targeted for removal, as surgical morbidity and c...

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Bibliographic Details
Main Authors: Acerbo, E. (Author), Bartolomei, F. (Author), Botzanowski, B. (Author), Carrère, M. (Author), Carron, R. (Author), Gross, R.E (Author), Jirsa, V. (Author), Missey, F. (Author), Safieddine, S. (Author), Trébuchon, A. (Author), Vanzetta, I. (Author), Weber, P. (Author), Williamson, A. (Author)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
ablation
adult
animal experiment
animal model
animal tissue
Article
blood brain barrier
brain edema
brain hemorrhage
controlled study
dendrite
dendritic cell
electroporation
epilepsy
epileptic discharge
epileptic focus
kindled seizure
mouse
nerve cell necrosis
nonhuman
nonthermal irreversible electroporation
reinnervation
resective surgery
seizure
tissue regeneration
two photon
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