Molecular interaction of ricin-a with caspase-3, caspase-8, caspase-9 and autophagy-related gene5 (Atg5) to understand its role as anticancer agent
The stimulation of caspases, i.e. intracellular cysteine proteases which cleave their substrates at aspartic acid residues, can lead to apoptosis. Autophagy, the regulated cellular degradation, is commenced from the engulfment of unwanted cytoplasmic content, followed by the fusion with the lysosome...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |