Genetic and compound screens uncover factors modulating cancer cell response to indisulam

Genetic and compound screens uncover factors modulating cancer cell response to indisulam

Discovering biomarkers of drug response and finding powerful drug combinations can support the reuse of previously abandoned cancer drugs in the clinic. Indisulam is an abandoned drug that acts as a molecular glue, inducing degradation of splicing factor RBM39 through interaction with CRL4DCAF15 Her...

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Bibliographic Details
Main Authors: Beijersbergen, R.L (Author), Bernards, R. (Author), De Conti, G. (Author), Dos Santos Dias, M. (Author), Groot, K. (Author), Jochems, F. (Author), Leite de Oliveira, R. (Author), Lieftink, C. (Author), Morris, B. (Author), Mulero-Sánchez, A. (Author), Pogacar, Z. (Author), Roosen, M. (Author), Thijssen, B. (Author), Velds, A. (Author), Wardak, L. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
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