Phylogenetic profiling resolves early emergence of PRC2 and illuminates its functional core

Polycomb repressive complex 2 (PRC2) is involved in maintaining transcriptionally silent chromatin states through methylating lysine 27 of histone H3 by the catalytic subunit enhancer of zeste [E(z)]. Here, we report the diversity of PRC2 core subunit proteins in different eukaryotic supergroups wit...

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Bibliographic Details
Main Authors: Mozgová, I. (Author), Oborník, M. (Author), Sharaf, A. (Author), Vijayanathan, M. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
Online Access:View Fulltext in Publisher