Beneficial effects of metformin on haloperidol-induced motor deficits in rats. A behavioral assessment
Objective: One of the most common side effects of haloperidol is the extrapyramidal syndrome, resulting from inhibition of nigrostriatal dopaminergic circuits and mitochondrial dysfunction due to structural similarities to pyridinium derivative, MPP+ that induce oxidative stress. In exchange, the us...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |