Stereoselective reduction of 1-benzyl-3,3-dimethyl-5-methylenepyrrolidine-2,4-dione using sodium borohydride with selected metal chlorides

1-benzyl-3,3-dimethyl-5-methylenepyrrolidine-2,4-dione is an intermediate product produced in the synthesis towards the natural bioactive compound, zopfiellamide A. This compound was synthesized via four main steps including dimethylations, addition with CuBr2, cyclization with benzylamine and react...

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Bibliographic Details
Main Authors: Hamzah, A.S (Author), Jumali, N.S (Author), Mohamad, H. (Author), Shaameri, Z. (Author)
Format: Article
Language:English
Published: Malaysian Society of Analytical Sciences 2017
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