Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection

Yeast metabolic innovations emerged via expanded metabolic network and gene positive selection

Yeasts are known to have versatile metabolic traits, while how these metabolic traits have evolved has not been elucidated systematically. We performed integrative evolution analysis to investigate how genomic evolution determines trait generation by reconstructing genome-scale metabolic models (GEM...

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Bibliographic Details
Main Authors: Chen, Y. (Author), Domenzain, I. (Author), Ji, B. (Author), Kerkhoven, E.J (Author), Li, F. (Author), Li, G. (Author), Lu, H. (Author), Nielsen, J. (Author), Wang, H. (Author), Yu, R. (Author), Yuan, L. (Author)
Format: Article
Language:English
Published: John Wiley and Sons Inc 2021
Subjects:
article
Crabtree effect
Evolution, Molecular
gene duplication
Gene Duplication
Gene Transfer, Horizontal
genetics
genome
Genome
genome analysis
genome-scale metabolic models
heat tolerance
horizontal gene transfer
metabolic innovation
Metabolic Networks and Pathways
metabolism
molecular evolution
multigene family
nonhuman
phenotypic variation
Saccharomyces cerevisiae
simulation
systems biology
yeast
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