Rare copy number variants identified suggest the regulating pathways in hypertension-related left ventricular hypertrophy

Rare copy number variants identified suggest the regulating pathways in hypertension-related left ventricular hypertrophy

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Left ventricular hypertrophy (LVH) is an independent risk factor for cardiovascular morbidity and mortality, and a powerful predictor of adverse cardiovascular outcomes in the hypertensive patients. It has complex multifactorial and polygenic basis for its pathogenesis. We hypothesized that rare cop...

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Bibliographic Details
Main Authors: Basir, F. (Author), Boon-Peng, H. (Author), Danuri, N. (Author), Jusoh, J.A.M (Author), Majid, F. (Author), Marshall, C.R (Author), Scherer, S.W (Author), Thiruvahindrapuram, B. (Author), Yusoff, K. (Author)
Format: Article
Language:English
Published: Public Library of Science 2016
Subjects:
adult
Article
case control study
Case-Control Studies
complication
controlled study
copy number variation
DNA Copy Number Variations
female
Female
gene frequency
Gene Frequency
gene ontology
Gene Ontology
gene regulatory network
Gene Regulatory Networks
genetic association
Genetic Association Studies
genetic association study
genetic predisposition
Genetic Predisposition to Disease
genetic susceptibility
genetic variability
genetics
heart left ventricle hypertrophy
heritability
human
Humans
hypertension
Hypertension
Hypertrophy, Left Ventricular
major clinical study
male
Male
middle aged
Middle Aged
molecular pathology
signal transduction
Signal Transduction
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