Network analysis of toxin production in Clostridioides difficile identifies key metabolic dependencies

Network analysis of toxin production in Clostridioides difficile identifies key metabolic dependencies

Clostridioides difficile pathogenesis is mediated through its two toxin proteins, TcdA and TcdB, which induce intestinal epithelial cell death and inflammation. It is possible to alter C. difficile toxin production by changing various metabolite concentrations within the extracellular environment. H...

Full description

Bibliographic Details
Main Authors: Jenior, M.L (Author), Kolling, G.L (Author), Papin, J.A (Author), Powers, D.A (Author)
Format: Article
Language:English
Published: NLM (Medline) 2023
Subjects:
bacterial protein
Bacterial Proteins
bacterial toxin
Bacterial Toxins
Clostridioides
Clostridioides difficile
enterotoxin
Enterotoxins
metabolism
Online Access:View Fulltext in Publisher
View in Scopus

Internet

View Fulltext in Publisher
View in Scopus

Similar Items