Multiple nutrient transporters enable cells to mitigate a rate-affinity tradeoff

Eukaryotic genomes often encode multiple transporters for the same nutrient. For example, budding yeast has 17 hexose transporters (HXTs), all of which potentially transport glucose. Using mathematical modelling, we show that transporters that use either facilitated diffusion or symport can have a r...

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Bibliographic Details
Main Authors: Correia, K. (Author), Montaño-Gutierrez, L.F (Author), Swain, P.S (Author)
Format: Article
Language:English
Published: Public Library of Science 2022
Online Access:View Fulltext in Publisher