Predicting the functional impact of KCNQ1 variants with artificial neural networks

Recent advances in experimental and computational protein structure determination have provided access to high-quality structures for most human proteins and mutants thereof. However, linking changes in structure in protein mutants to functional impact remains an active area of method development. I...

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Bibliographic Details
Main Authors: George, A.L., Jr (Author), Kuenze, G. (Author), Meiler, J. (Author), Phul, S. (Author), Sanders, C.R (Author), Vanoye, C.G (Author)
Format: Article
Language:English
Published: Public Library of Science 2022
Online Access:View Fulltext in Publisher