Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy

Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy

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Scattering can seriously affect the highly sensitive detection and quantitative analysis of chemical substances in scattering media and becomes a significant challenge for in vivo application of Raman spectroscopy. In this study, we demonstrated a proof of concept for using the self-reconstructing B...

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Bibliographic Details
Main Authors:	Chen, X. (Author), Li, L. (Author), Ren, F. (Author), Song, Y. (Author), Wang, H. (Author), Wang, L. (Author), Wang, N. (Author), Zeng, Q. (Author), Zeng, T. (Author), Zhu, S. (Author)
Format:	Article
Language:	English
Published:	Optica Publishing Group (formerly OSA) 2022
Subjects:	animal experiment animal tissue Article Bessel beam Bessel beam Raman spectroscopy Biological tissues Chemical detection Chemical sensing Chemical sensors Chemical substance controlled study drug analysis drug concentration drug determination feasibility study Gaussian beam Raman spectroscopy Gaussian beams Highly sensitive detections In-vivo Laser beams light intensity light scattering mouse nonhuman paracetamol Proof of concept quantitative analysis Raman scattering Raman spectrometry Raman spectroscopy Scattering medium spectroscopy Spectrum analysis thickness Tissue tissue slice Tissue slice Vivo applications
Online Access:	View Fulltext in Publisher

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