Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy

Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy

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Scattering can seriously affect the highly sensitive detection and quantitative analysis of chemical substances in scattering media and becomes a significant challenge for in vivo application of Raman spectroscopy. In this study, we demonstrated a proof of concept for using the self-reconstructing B...

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Bibliographic Details
Main Authors: Chen, X. (Author), Li, L. (Author), Ren, F. (Author), Song, Y. (Author), Wang, H. (Author), Wang, L. (Author), Wang, N. (Author), Zeng, Q. (Author), Zeng, T. (Author), Zhu, S. (Author)
Format: Article
Language:English
Published: Optica Publishing Group (formerly OSA) 2022
Subjects:
animal experiment
animal tissue
Article
Bessel beam
Bessel beam Raman spectroscopy
Biological tissues
Chemical detection
Chemical sensing
Chemical sensors
Chemical substance
controlled study
drug analysis
drug concentration
drug determination
feasibility study
Gaussian beam Raman spectroscopy
Gaussian beams
Highly sensitive detections
In-vivo
Laser beams
light intensity
light scattering
mouse
nonhuman
paracetamol
Proof of concept
quantitative analysis
Raman scattering
Raman spectrometry
Raman spectroscopy
Scattering medium
spectroscopy
Spectrum analysis
thickness
Tissue
tissue slice
Tissue slice
Vivo applications
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