Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance

Background: Immune checkpoint blockade (ICB) therapy has revolutionized the treatment of lung squamous cell carcinoma (LUSC). However, a significant proportion of patients with high tumour PD-L1 expression remain resistant to immune checkpoint inhibitors. To understand the underlying resistance mech...

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Bibliographic Details
Main Authors: Chen, K. (Author), Li, W. (Author), Lin, C. (Author), Wang, Y. (Author), Yang, M. (Author), Zhang, H. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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Online Access:View Fulltext in Publisher