Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance
Background: Immune checkpoint blockade (ICB) therapy has revolutionized the treatment of lung squamous cell carcinoma (LUSC). However, a significant proportion of patients with high tumour PD-L1 expression remain resistant to immune checkpoint inhibitors. To understand the underlying resistance mech...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2022
|
Subjects: | |
Online Access: | View Fulltext in Publisher |