Prenatal diagnosis and genetic counseling of a uniparental isodisomy of chromosome 8 with no phenotypic abnormalities
Background: Uniparental disomy (UPD) refers to an epigenomic abnormality in which both copies of, or a part of, a homologous pair of chromosomes are inherited from one parent. UPD arises via a number of mechanisms, including monosomic and trisomic rescue (in embryonic development), incomplete segreg...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BioMed Central Ltd
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |