Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injury

Macrophage-based delivery of interleukin-13 improves functional and histopathological outcomes following spinal cord injury

Background: Spinal cord injury (SCI) elicits a robust neuroinflammatory reaction which, in turn, exacerbates the initial mechanical damage. Pivotal players orchestrating this response are macrophages (Mφs) and microglia. After SCI, the inflammatory environment is dominated by pro-inflammatory Mφs/mi...

Full description

Bibliographic Details
Main Authors: Dooley, D. (Author), Erens, C. (Author), Hendrix, S. (Author), Lemmens, S. (Author), Ponsaerts, P. (Author), Quarta, A. (Author), Sanchez, S. (Author), Scheijen, E. (Author), Sommer, D. (Author), Van Breedam, E. (Author), Van Broeckhoven, J. (Author), Vidal, P.M (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
CNS trauma
Immunomodulation
Interleukin-13
Macrophages
Neuroinflammation
Neurospheroids
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items