SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling

Background: Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. SEMA4D is a 150 kDa transmembrane protein that belongs to the IV class of the subfamily of semaphorin family. Previous studies have reported that SEMA4D is a multifunctional target in many solid tumors, inv...

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Bibliographic Details
Main Authors: Feng, X. (Author), Liu, J. (Author), Liu, L. (Author), Liu, M. (Author), Liu, X. (Author), Luo, J. (Author), Nie, Z. (Author), Yang, L. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
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