Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia

Acute Myeloid Leukaemia (AML) is a haematological malignancy showing a hypervariable landscape of clinical outcomes and phenotypic differences, explainable by heterogeneity at the cellular and molecular level. Among the most common genomic alterations, CBFB-MYH11 rearrangement and FLT3-ITD gene muta...

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Main Authors: Ciliberto, G. (Author), De Bellis, E. (Author), De Nicola, F. (Author), Divona, M. (Author), Fanciulli, M. (Author), Goeman, F. (Author), Guarnera, L. (Author), Lo Iudice, G. (Author), Massacci, A. (Author), Ottone, T. (Author), Pallocca, M. (Author), Savi, A. (Author), Voso, M.T (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Online Access:View Fulltext in Publisher