Bias amplification in the g-computation algorithm for time-varying treatments: a case study of industry payments and prescription of opioid products

Background: It is often challenging to determine which variables need to be included in the g-computation algorithm under the time-varying setting. Conditioning on instrumental variables (IVs) is known to introduce greater bias when there is unmeasured confounding in the point-treatment settings, an...

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Bibliographic Details
Main Authors: Goto, A. (Author), Inoue, K. (Author), Kondo, N. (Author), Shinozaki, T. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2022
Subjects:
Online Access:View Fulltext in Publisher